Microbial and Enzyme Kinetics

Module Guide

Contents

1. Schedule
2. Recommended Reading
3. Module Description
4. Assessment
5. Late Submission of work
6. Plagiarism
7. Tutorial Problems
8. Home Page

Recommended Reading

Price N C & Dwek R A, (2001), Principles & Problems in Physical Chemistry for Biochemists, 3^rd E^dn, Oxford University Press

Fersht A, Enzyme Structure & Mechanism, W H Freeman & Co. (May now be out of print)

Doran, P.M. (1995), Bioprocess Engineering Principles, Academic Press,.

Notes are provided here for the Enzyme kinetics topics. Select the relevant link from the menu on the right.

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Module Description

This module looks at basic rate equations for microbial growth and enzyme kinetics and looks at them in terms of fermenter/reactor design. Monod growth kinetics, substrate consumption, and product formation are investigated. Michaelis-Menten kinetics are revisited and extended to inhibition, two substrate reactions and enzyme inactivation. The application of rate equations to fermenter design provides a link between the biochemical and engineering applications.

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Assessment:

Coursework:	40%
Exam:	60%

Coursework will consist of:

	Weighting	Submit by end of
Enzyme Kinetics	20%	During tutorials
Microbial Kinetics	20%	Week 8

The coursework in Microbial Kinetics will be based on the kinetic aspects of the syllabus encountered during the first part of the semester. It will consist of problems to be completed in the students own time and submitted by the end of week 8.

Coursework in Enzyme Kinetics will comprise problems to be completed and submitted during the enzyme kinetics tutorials.

Examination format

The examination will be of 2 hours duration and you will be expected to answer 4 from 6 questions. The examination paper will be divided into two sections and you will be expected to answer at least one question from each section. You will be given a formula sheet.

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Late submission of work.

Written coursework should be submitted to the assignment off ice (M208) by the due date with the declaration signed. Work submitted late will be subject to the following penalties.

• Up to one week late and the maximum grade achievable will be D.
• More than one week late and the assignment will normally be awarded no mark at all.

If, for any reason, you are unable to meet the original deadline, you should contact the module tutor who may set a new deadline if the reason is considered valid.

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Plagiarism:

Plagiarism is passing off the work of others as your own and as such is a form of cheating and will be penalised. There are two main mechanisms by which you may avoid plagiarism.

• Use your own words at all times in your coursework
• Acknowledge all your sources through proper referencing of your work.

Details of University regulations and procedures on plagiarism are in your student handbook.